Cellular Sensors of Feast and Famine
Posted: Sun Mar 22, 2009 5:39 am
In the Blueprint, I detail two strategies (Feast and Famine Phases) that result in a combustion engine-like effect on your metabolism.
Following then, is a peak into some research studies detailing just what guages your cells use to make the complex metabolic adjustments The Blueprint creates:
1.Ruderman NB, et al. Malonyl-CoA, fuel sensing, and insulin resistance. Am J Physiol. 1999;276:E1–E18. [PubMed]
2.Marshall S, Bacote V, Traxinger RR. Complete inhibition of glucose-induced desensitization of the glucose transport system by inhibitors of mRNA synthesis. Evidence for rapid turnover of glutamine:fructose-6-phosphate amidotransferase. J Biol Chem. 1991;266:10155–10161. [PubMed]
3.Obici S, et al. Identification of a biochemical link between energy intake and energy expenditure. J Clin Invest. 2002;109:1599–1605. doi:10.1172/JCI200215258. [PubMed]
4.Bouchard C, et al. The response to long-term overfeeding in identical twins. N Engl J Med. 1990;322:1477–1482. [PubMed]
Take away: By rotating each time-sensitive dietary phase shift, The Blueprint keeps you way ahead of your body and progress ongoing.
Following then, is a peak into some research studies detailing just what guages your cells use to make the complex metabolic adjustments The Blueprint creates:
1.Ruderman NB, et al. Malonyl-CoA, fuel sensing, and insulin resistance. Am J Physiol. 1999;276:E1–E18. [PubMed]
2.Marshall S, Bacote V, Traxinger RR. Complete inhibition of glucose-induced desensitization of the glucose transport system by inhibitors of mRNA synthesis. Evidence for rapid turnover of glutamine:fructose-6-phosphate amidotransferase. J Biol Chem. 1991;266:10155–10161. [PubMed]
3.Obici S, et al. Identification of a biochemical link between energy intake and energy expenditure. J Clin Invest. 2002;109:1599–1605. doi:10.1172/JCI200215258. [PubMed]
4.Bouchard C, et al. The response to long-term overfeeding in identical twins. N Engl J Med. 1990;322:1477–1482. [PubMed]
Take away: By rotating each time-sensitive dietary phase shift, The Blueprint keeps you way ahead of your body and progress ongoing.