Good question, JML.
MASS PRO is as undenatured as possible, so the natural enzymes remain intact. As Rob mentioned, none of the typical "bad/non assimilation" issues like gas and bloating are seen with MASS PRO.
That said, if you are looking for a full range medical grade Digestive Enzyme, then look no further than Alkaplex Green- https://bodybuildingsupplements.com/digestive_enzymes.html